Breast Milk and Formula in One Bottle: What Sources Say
The short answer
The CDC pages on breast milk storage and on formula preparation do not mention putting breast milk and formula in one bottle. Other pages we opened do, and they differ: some say to keep them separate, some describe how to combine them. Table 1 gives each page's wording. Ask your pediatrician about your baby.
Key takeaways
- The CDC pages on breast milk storage (updated 2026-08-14) and on formula preparation (dated 2026-05-14) do not mention mixing the two.
- A CDC emergency feeding page says to give breast milk first, then formula. It does not mention one bottle.
- La Leche League Canada and KellyMom say to keep them separate. Similac and Bobbie describe how to combine them. Enfamil says to ask your pediatrician.
- No health agency, health service or charity page we opened gives a time for a mixed bottle.
- One bottle at one sitting is one feed in a log: write the parts, the total offered, what was left and what the baby drank.
The times for leftover breast milk are on our leftover breast milk guide. This page covers what sources say about one bottle, and how to write a combo bottle down.
What do official sources say about mixing breast milk and formula in one bottle?
The health agency pages we opened say nothing about one bottle. Table 1 also lists a charity, a lactation site and three formula makers, each labelled by type. All rows were opened on 2026-10-25.
Table 1. What named sources say about mixing breast milk and formula
| Source | Country/year | What it says about mixing | What it says about order or water |
|---|---|---|---|
| CDC, Breast milk storage and preparation (health agency) | US. Published 2024-05-15, updated 2026-08-14 | Not stated. The page does not mention formula. | Not stated |
| CDC, Infant formula preparation and storage (health agency) | US. Dated 2026-05-14 | Not stated. The page does not mention breast milk. | For formula alone: “Always measure the water first and then add the powder.” |
| CDC, Prepare and Store Powdered Infant Formula in an Emergency (health agency, emergency feeding page) | US. Published 2024-05-15, updated 2026-08-10 | Not stated for one bottle. | Under “Feeding tips”: “If you feed your baby with both breast milk and powdered formula, breastfeed or feed your baby breast milk first, then feed the formula.” |
| AAP HealthyChildren.org, Tips for Freezing & Refrigerating Breast Milk (professional body) | US. Page shows “Last Updated 7/7/2025” | Not stated. The article does not mention formula. | Not stated |
| NHS, Mixed feeding (health service) | UK. No date shown | Not stated. It describes mixed feeding as using “either expressed breast milk or infant formula”. | Not stated |
| NHS 111 Wales, How to combine breast and bottle feeding (health service) | Wales. “Last Updated: 13/06/2023” | Not stated | Not stated |
| NHS Highland, Mixed (combination) feeding (health board) | Scotland. “Last updated: 26 November 2025” | Not stated for one bottle. About feeds: “Try to separate formula feeds from breastfeeds, if possible.” | Not stated |
| NCT, Mixed feeding (charity) | UK. “Last reviewed: 11 September 2026” | Not stated. It covers separate feeds and top ups. | Not stated |
| La Leche League Canada, Should you mix human milk with formula? (charity) | Canada. “Updated 2025” | “It is recommended that formula not be mixed with human milk for the following reasons:” and “It is recommended that you feed human milk separate from formula to maximize the benefits of human milk.” It adds: “If you mix your milk with formula and your baby doesn’t finish the bottle (or cup), it must be discarded.” The page lists further reasons. | Not stated |
| KellyMom, How to bottle feed the breastfed baby (lactation information site, author Eva Lyford) | US. “Updated on August 22, 2026” | “If you are using both breastmilk and infant formula during the same feed, it’s best not to mix them in the same bottle.” | “Feed the breastmilk, then follow with formula.” |
| Similac, formula introduction page (formula maker, manufacturer guidance) | US. No date shown | “If needed, to help your baby accept formula, you can mix breast milk and prepared formula in the same bottle.” | “Just make sure that you follow the formula mixing instructions and add the appropriate amount of water to make formula from powder or concentrated liquid before you mix with breast milk.” |
| Bobbie, Can you mix breast milk and formula? (formula maker, blog article, no reviewer named) | US. Published 2025-10-09, updated 2026-06-17 | “Breast milk and prepared formula are combined in the same bottle before feeding.” The article names this “same-bottle mixing”. | “always prepare infant formula exactly as directed first.” and “Never stir powdered or concentrated formula directly into expressed breast milk.” For a bottle in use it says “the one-hour rule applies” and “after 60 minutes, toss whatever’s left.” |
| Enfamil, Can you mix breast milk and formula? (formula maker, manufacturer guidance) | US. No date shown | “it’s always best to ask your pediatrician how to handle mixing breast milk and formula.” It also says: “There are some schools of thought that recommend keeping breast milk and formula separate.” | Not stated |
“Not stated” means the page, as we read it, has no sentence on the point. It does not mean the answer is no. The table picks no winner and averages nothing. The formula-maker rows are web pages from the makers, not a product label, and we did not open a label. For your formula, read the label.
We searched for AAP, WHO and Mayo Clinic pages on putting both in one bottle and did not open one. Their absence from table 1 says nothing about what those bodies think. How we source explains how a page gets into a table.
Why do parents get different answers?
Because the pages differ. In table 1, the health agency and health service pages are silent on one bottle, La Leche League Canada and KellyMom say to keep them separate, and the formula makers describe how to combine them or send you to your pediatrician.
Individual clinicians quoted in parenting magazines add more views. In a Romper article (by Jessica Booth, updated Feb. 20, 2024), pediatrician Maya Muñoz Mahmood, described there as a Fellow of the American Academy of Pediatrics, says: “As a broad rule, I don’t recommend mixing them in the same bottle.” That is one clinician’s personal view as quoted by a magazine. It is not AAP policy, and the AAP page in table 1 does not mention mixing.
The CDC’s “breast milk first, then formula” line is on its emergency feeding page, not on the two storage pages. It is about the order of feeds. The page does not mention one bottle.
What changes about leftover milk when a bottle is mixed?
No health agency, health service or charity page in table 1 gives a time for a mixed bottle, so this page gives none in its own voice. The one time in table 1 is a formula maker’s. The times for leftover breast milk, quoted from named sources, are on the leftover guide for breast milk. Fresh and thawed breast milk times from named sources are in the storage times from named sources table.
The CDC’s 2 hours is written for leftover breast milk. The CDC formula page gives separate times for prepared formula: “within 2 hours of preparation and within one hour from when feeding begins”. Bobbie, a formula maker, gives its own wording for a mixed bottle in table 1. The CDC pages do not give a time for a mixed bottle.
How do you write down a combo bottle?
Write one bottle at one sitting as one feed, with the parts and a total. Table 2 shows three ways.
Table 2. Three ways to write down a combo bottle
| Way | What you write | Example row | Counts as | What it cannot tell you |
|---|---|---|---|---|
| One line with a total | Total offered, left, drank | 3 fl oz (about 90 ml) offered, 0.5 fl oz (about 15 ml) left, 2.5 fl oz (about 75 ml) drank | 1 feed | How much of each source the baby drank |
| Two lines, one per source | A line for pumped milk and a line for formula, both tagged “bottle 1”. Write left once, for the bottle. | Line 1: pumped milk 2 fl oz (about 60 ml). Line 2: formula 1 fl oz (about 30 ml). Left: 0.5 fl oz (about 15 ml) | 1 feed (two lines, one tag) | Left and drank per source, unless you estimate |
| One bottle with parts | One row: each part, then the total offered, then left and drank | 2 fl oz (about 60 ml) pumped milk + 1 fl oz (about 30 ml) formula = 3 fl oz (about 90 ml) offered. Left 0.5 fl oz (about 15 ml). Drank 2.5 fl oz (about 75 ml) | 1 feed | How much of each source the baby drank |
In words, one line reads: breast milk 2 fl oz (about 60 ml) + formula 1 fl oz (about 30 ml) = 3 fl oz (about 90 ml) offered.
Example: pumped milk 2 fl oz (about 60 ml) + formula 1 fl oz (about 30 ml) = 3 fl oz (about 90 ml) offered. When the baby stops, 0.5 fl oz (about 15 ml) is left. Drank: 3 - 0.5 = 2.5 fl oz, or 90 - 15 = 75 ml. (1 fl oz is 29.5735 ml, so 3 fl oz is 88.7 ml. The ml figures here are rounded to the nearest 5 ml.)
If you want a number for each source, one method is to split what the baby drank in proportion to what went into the bottle. Pumped milk was 2 of 3 parts and formula was 1 of 3 parts:
- Pumped milk: 2/3 x 75 ml = 50 ml (about 1.7 fl oz).
- Formula: 1/3 x 75 ml = 25 ml (about 0.85 fl oz).
This is an estimate. It assumes the bottle was mixed evenly and that the baby took the same share of each part.
Logging one bottle as one feed counts that sitting once. Two separate entries for one bottle would count one feed twice: six combo bottles in a day read as 6 feeds, not 12. The printable bottle feeding log has a mixed-bottle line for this. Rememilk, the bottle log we are building, is in development. The printable works without it.
What if you cannot measure breastfeeding?
A nursing session has no ml you can read, so write it as “not measured” with the minutes per side, never as 0 ml. A day total then reads “X ml measured + N nursing sessions not measured”. Example: “450 ml (about 15 fl oz) measured + 3 nursing sessions not measured”. The printable has a nursing row for this.
What this page is, and what it is not
We are parents, not medical professionals. The page reports what named sources say, and the sentences in table 1 belong to those sources. Ask your pediatrician or a lactation consultant about your baby's feeding. If your baby was born early or is unwell, ask your care team.
Sources change. Each entry in the Sources list has a "Last checked" date, and the CDC pages were updated in May and August 2026. Read who writes here for the author's role.
Frequently asked questions
Is it ok to put breast milk and formula in the same bottle?
The CDC pages we read do not say. Other pages we opened give different answers: La Leche League Canada and KellyMom say to keep them separate, Similac and Bobbie describe how to combine them, and Enfamil says to ask your pediatrician. Table 1 has the wording of each.
Do you mix breast milk with formula or keep the bottles separate?
Some formula-maker and lactation pages in table 1 describe combining in one bottle or keeping the milks apart, and this page does not pick one. Your pediatrician or a lactation consultant can advise on your baby.
How do I log a bottle that has both?
Write each part, the total offered, what was left and what the baby drank. Example: 2 fl oz (about 60 ml) pumped milk + 1 fl oz (about 30 ml) formula = 3 fl oz (about 90 ml) offered, 0.5 fl oz (about 15 ml) left, 2.5 fl oz (about 75 ml) drank.
Do I count a combo bottle as one feed or two?
As one feed, if it was one bottle at one sitting. That is a logging choice that avoids counting the same feed twice. Table 2 shows three ways to write the parts.
Does a mixed bottle follow the 2 hour leftover guidance?
The health agency pages we opened do not say. The CDC's 2 hours is written for leftover breast milk, and its formula page gives separate times for prepared formula. Neither mentions a mixed bottle.
Do you add breast milk to formula powder or to prepared formula?
The CDC formula page does not mention breast milk. For formula alone it says: "Always measure the water first and then add the powder." Similac and Bobbie both say to prepare the formula first and then add breast milk, and Bobbie adds: "Never stir powdered or concentrated formula directly into expressed breast milk."
Sources
- CDC, Breast milk storage and preparation
- CDC, Infant formula preparation and storage
- CDC, Prepare and Store Powdered Infant Formula in an Emergency
- AAP HealthyChildren.org, Tips for Freezing & Refrigerating Breast Milk
- NHS, Mixed feeding
- NHS 111 Wales, How to combine breast and bottle feeding
- NHS Highland, Mixed (combination) feeding
- NCT, Mixed feeding
- La Leche League Canada, Should you mix human milk with formula?
- KellyMom, How to bottle feed the breastfed baby
- Similac, formula introduction page (formula maker)
- Bobbie, Can you mix breast milk and formula? (formula maker blog, no reviewer named)
- Enfamil, Can you mix breast milk and formula? (formula maker)
- Romper, by Jessica Booth (parenting magazine)
Rememilk is a bottle milk log in development
It keeps offered, left and drank for every bottle, and nursing you cannot measure.